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折扣/货期| 货号：75780-1 mg | 规格：1 mg | 目录价：￥255 |
| 货号：75780-10 mg | 规格：10 mg | 目录价：￥1742 |
| 货号：75780-100 mg | 规格：100 mg | 目录价：￥12891 |
| 货号：75780-5 mg | 规格：5 mg | 目录价：￥992 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HET0016
别名:
N-hydroxy-N'-(4-n-butyl-2-methylphenyl)Formamidine
产品描述:
20-HETE is a major biologically active CYP450 metabolite of arachidonic acid in the kidney and liver. It regulates renal vascular and tubular functions as well as vascular tone in the cerebral circulation.{12466,12470,12468,12467,9023} HET0016 is an inhibitor of 20-HETE formation in human renal microsomes with an IC50 of 8.9 nM, selectively inhibiting CYP4A and 4F isoforms.{8946,12469} HET0016 inhibits CYP2C9, CYP2D6, and CYP3A4, enzymes important in drug metabolism, significantly less effectively with IC50 values in the µM range. The IC50 values for inhibition of COX and epoxyeicosatrienoic acids (EETs) formation are 2.3 and 2.8 µM, respectively.{8946}
保存温度:
-20
运输温度:
-20
预期分子量:
206.3
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
339068-25-6
分子式:
C12H18N2O
促销活动
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