HGS Antibody-多抗-深圳欣博盛生物科技有限公司

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HGS Antibody

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：61-121

规格：400 ul

目录价：￥8687.25

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

HGS Antibody

别名:

Hepatocyte growth factor-regulated tyrosine kinase substrate, Hrs, Protein pp110, HGS, HRS

反应种属:

Human,Mouse

宿主来源:

Rabbit

实验应用:

WB,IHC-P

同种型:

Rabbit Ig

克隆性:

Polyclonal

纯化方式:

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

偶联:

Unconjugated

产品浓度:

batch dependent

保存温度:

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

Supplied in PBS with 0.09% (W/V) sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

HGS is involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. It could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. HGS may concentrate ubiquitinated receptors within clathrin-coated regions. It is involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM. This complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. HGS may contribute to the efficient recruitment of SMADs to the activin receptor complex.

Accession #:

O14964

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