深圳欣博盛生物科技有限公司 a1

Histone Deacetylase 8 Antibody / HDAC8
货号:RQ6773 规格:100 ug 目录价:¥6488.05
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Histone Deacetylase 8 Antibody / HDAC8
产品描述:
HDAC8, Histone deacetylase 8, is an enzyme that in humans is encoded by the HDAC8 gene, and is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Sequence analysis predicted that the 377-amino acid HDAC8 protein contains the 9 conserved HDAC blocks that are presumably important for catalytic function. HDAC8 shares 54% sequence similarity with HDAC1 and HDAC2 and 39% similarity with HDAC3, making it a class I HDAC. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, Direct ELISA
同种型:
Rabbit IgG
免疫原:
Recombinant human protein (amino acids D29-E347) was used as the immunogen for the Histone Deacetylase 8 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the Histone Deacetylase 8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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