官网链接
折扣/货期| 货号：AG-CR1-3620-M005 | 规格：5 mg | 目录价：￥960 |
| 货号：AG-CR1-3620-M025 | 规格：25 mg | 目录价：￥1920 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ibrutinib
别名:
PCI-32765
产品描述:
Potent and highly selective Bruton's tyrosine kinase (BTK) inhibitor. Orally bioavailable and irreversible inhibitor of BTK (IC50 = 0.5 nM) with antineoplastic activity. Binds to and irreversibly inhibits BTK activity, preventing B cell activation and B cell-mediated signaling. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. Shown to inhibit autophosphorylation of BTK (IC50 = 11nM), phosphorylation of PLCgamma (IC50 = 29nM), a substrate of BTK and phosphorylation of ERK (IC50 = 13nM).
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
440.5
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
936563-96-1
分子式:
C25H24N6O2
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