| 货号:24107-1 mg | 规格:1 mg | 目录价:¥1273 |
| 货号:24107-10 mg | 规格:10 mg | 目录价:¥10519 |
| 货号:24107-5 mg | 规格:5 mg | 目录价:¥5883 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
IDH305
产品描述:
A potent and selective inhibitor of mutant IDH1 (IC50s = 27, 28, and 6,140 nM for recombinant IDH1R132H, IDH1R132C, and wild-type IDH1, respectively); reduces 2-HG production and inhibits growth of MCF-10A-IDH1R132H/+ cells in a concentration-dependent manner; reduces concentration of tumor 2-HG in an HCT116-IDH1R132H/+ mouse xenograft model (200 mg/kg); suppresses 2-HG production and reduces tumor progression in an HMEX2838-IDH1R132C patient-derived melanoma mouse xenograft model (300 mg/kg)
保存温度:
-20
运输温度:
-20
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1628805-46-8
分子式:
C23H22F4N6O2
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