| 货号:REV-31-1025-MK-KI01 | 规格:1 Set | 目录价:¥7910 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
IgD (human) Matched Antibody Pair
别名:
Immunoglobulin D
产品描述:
The Human IgD Matched Antibody Pairs is specific to Human IgD and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data.Immunoglobulin D (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B-lymphocytes where it is usually co-expressed with IgM. IgD is also produced in a secreted form that is found in very small amounts in blood serum, representing 0.25% of immunoglobulins in serum. Secreted IgD is produced as a monomeric antibody with two heavy chains of the delta (delta) class, and two Ig light chains. In B cells, the function of IgD is to signal the B cells to be activated. By being activated, B cells are ready to take part in the defense of the body as part of the immune system. IgD was found to bind to basophils and mast cells and activate these cells to produce antimicrobial factors to participate in respiratory immune defense in humans. It also stimulates basophils to release B cell homeostatic factors.
靶标/特异性:
The antibody pair detects only human IgD. It does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG. There is no cross reactivity to any other immunoglobulins or IgG subclasses.
保存温度:
+4°C
运输温度:
BI
产地:
瑞士
样本类型:
Serum
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