IkBa Antibody / IkB alpha-多抗-深圳欣博盛生物科技有限公司

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IkBa Antibody / IkB alpha

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R31704

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IkBa Antibody / IkB alpha

产品描述:

NFKBIA, also called IkBa or MAD-3, is one member of a family of cellular proteins that function to inhibit the NF-kB transcription factor. It inhibits NF-kB by masking the nuclear localization signals (NLS) of NF-kB proteins and keeping them sequestered in an inactive state in the cytoplasm. It moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. The effect of the nonpathogenic bacteria is specific to the SCF complex substrates beta Catenin and IkBa. This may help to explain the beneficial effects of treatment of inflammatory bowel disease with nonpathogenic probiotic enteric organisms. In addition, IkBa blocks the ability of NFkB transcription factors to bind to DNA, which is required for proper NFkB functioning.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

同种型:

Rabbit IgG

免疫原:

Human partial recombinant protein (AA 3-112) was used as the immunogen for this IkBa antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the IkBa antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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