官网链接
折扣/货期| 货号：19839-1 mg | 规格：1 mg | 目录价：￥737 |
| 货号：19839-10 mg | 规格：10 mg | 目录价：￥6633 |
| 货号：19839-5 mg | 规格：5 mg | 目录价：￥3511 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
iKIX1
产品描述:
An inhibitor of interactions between the transcription co-activator Mediator complex and the CgPdr1 transcription factor in the pathogen C. glabrata; inhibits the interaction between the KIX domain of the Mediator subunit CgGal11A and the activation domain of CgPdr1 (IC50 = 190.2 μM); inhibits ketoconazole-induced expression of CgPdr1-target genes involved in multidrug resistance and drug efflux in C. glabrata at 10 and 30 μM; increases the sensitivity of azole-resistant C. glabrata strains expressing CgPDR1 gain-of-function mutations to fluconazole and ketoconazole; decreases fungal burden in the kidney and spleen in a mouse model of infection with azole-sensitive or -resistant C. glabrata at 100 mg/kg when administered in combination with low and high doses of fluconazole, respectively
保存温度:
-20
运输温度:
-20
预期分子量:
303.2
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
656222-54-7
分子式:
C10H8Cl2N4OS
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询