深圳欣博盛生物科技有限公司 a1

IL-13 Recombinant Protein
品牌:ProSci LLC
货号:11-292 规格:0.05 mg 目录价:¥10126.35
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
IL-13 Recombinant Protein
别名:
IL13,ALRH,BHR1,MGC116786,MGC116788,MGC116789,P600,Interleukin-13
实验应用:
ELISA,WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
Tris with Glycine, Arginine and NaCl, pH7.5
产地:
美国
生产商:
Prosci
功能与背景:
Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a single-chain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. IL-13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction.
纯度:
>90% as determined by SDS-PAGE.
Accession #:
AAK53823.1
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