IL-1alpha (mouse) Matched Pair Detection Set-抗体对-深圳欣博盛生物科技有限公司

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IL-1alpha (mouse) Matched Pair Detection Set

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-46B-0004-KI01

规格：1 Set

目录价：￥7800

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL-1alpha (mouse) Matched Pair Detection Set

别名:

Interleukin-1alpha

产品描述:

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1alpha and IL-1beta. Although most activators fully rely on the inflammasome for IL-1alpha secretion, some induce the processing and secretion of IL-1alpha in an inflammasome-independent manner.

靶标/特异性:

Detects mouse IL-1alpha. Does not detect human IL-1alpha or mouse IL-1beta.

保存温度:

+4°C

运输温度:

产地:

瑞士

灵敏度:

10pg/ml

检测范围:

15.6 to 2000pg/ml

检测方法: