| 货号:18215-1 mg | 规格:1 mg | 目录价:¥1715.2 |
| 货号:18215-100 µg | 规格:100 µg | 目录价:¥428.8 |
| 货号:18215-5 mg | 规格:5 mg | 目录价:¥6472.2 |
| 货号:18215-500 µg | 规格:500 µg | 目录价:¥1179.2 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Iloprost
别名:
Ciloprost|ZK 36374
产品描述:
An IP and EP1 receptor agonist; selectively binds to IP and EP1 receptors (Ki = 11 nM for both) over EP2, EP4, DP, FP, and TP receptors (Kis = 1,870, 284, 1,035, 619, and 6,487 nM, respectively) but also binds to the EP3 receptor (Ki = 56 nM); increases cAMP levels in HEK293 cells expressing IP or EP3 receptors (EC50s = 0.37 and 27.5 nM, respectively); increases calcium levels in HEK293 cells expressing the EP1 receptor (EC50 = 0.3 nM); inhibits ADP-, thrombin-, and collagen-induced platelet aggregation in isolated human platelet-rich plasma (IC50s = 1.07, 0.71, and 0.24 nM, respectively); increases the time to occlusive coronary artery thrombosis in a porcine model of electrically induced coronary artery thrombosis at 100 ng/kg per minute; reduces right ventricular systolic pressure and reverses vascular remodeling in rats in a model of monocrotaline-induced chronic pulmonary hypertension at 130-1,300 ng/kg per minute
保存温度:
-20
运输温度:
-20
预期分子量:
360.5
产品形式:
A 1 mg/ml solution in methyl acetate
有效期:
730
纯度:
≥97%
CAS号:
78919-13-8
分子式:
C22H32O4
促销活动
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