深圳欣博盛生物科技有限公司 a1

IMM-H007
货号:38774-1 mg 规格:1 mg 目录价:¥764
货号:38774-10 mg 规格:10 mg 目录价:¥6017
货号:38774-25 mg 规格:25 mg 目录价:¥11283
货号:38774-5 mg 规格:5 mg 目录价:¥3390
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
IMM-H007
产品描述:
An AMPK activator and TGF-β1 antagonist; increases AMPK activity in HepG2 cell lysates from 1-100 µM; binds to TGF-β1 (Kd = 0.2098 µM) and inhibits the binding of TGF-β1 to TGFBR2 at 6 µM; increases cholesterol efflux in THP-1 macrophages incubated with isolated mouse ApoB-depleted serum ex vivo at 100 or 200 mg/kg; decreases serum levels of triglycerides, total cholesterol, and LDL cholesterol, as well as hepatic lipid accumulation, in a hamster model of high-fat diet-induced hyperlipidemia at 18 mg/kg; decreases fibrotic area in wild-type and AMPKα2-/- mice in a model of isoprenaline-induced cardiac fibrosis at 200 mg/kg; decreases atherosclerotic lesion area in ApoE-/- mice fed a Paigen diet
保存温度:
-20
运输温度:
-20
预期分子量:
485.5
产品形式:
A solid
纯度:
≥95%
CAS号:
1221412-23-2
分子式:
C22H23N5O8
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