深圳欣博盛生物科技有限公司 a1

INCB 3344
货号:28433-1 mg 规格:1 mg 目录价:¥1380
货号:28433-10 mg 规格:10 mg 目录价:¥9407
货号:28433-5 mg 规格:5 mg 目录价:¥5065
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
INCB 3344
产品描述:
An antagonist of CCR2 (IC50 = 10 nM); selective for CCR2 over a panel of G protein-coupled receptors, including CCR1 and CCR5, with IC50s values >1 µM; inhibits MCP-1-induced chemotaxis of WEHI-274 cells (IC50 = 10 nM); inhibits monocyte influx in a thioglycolate-induced mouse model of peritonitis at 60 and 100 mg/kg; decreases the expression of CCR2 mRNA in the ear and reduces ear swelling in a mouse model of delayed-type hypersensitivity reaction at 30, 50, and 100 mg/kg twice per day; prevents increases in or reduces macrophage levels in the spinal cord at 100 mg/kg per day beginning the day of immunization or seven days following immunization, respectively, in a mouse model of EAE
保存温度:
-20
运输温度:
-20
预期分子量:
577.592089
产品形式:
A solid
纯度:
≥95%
CAS号:
1262238-11-8
分子式:
C29H34F3N3O6
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