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折扣/货期| 货号：CDX-I0019-M001 | 规格：1 mg | 目录价：￥2212 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Indo 1-AM
别名:
Indo-1-(acetoxymethyl) ester; 4-(6-Carboxy-2-indolyl)-4'-methyl-2,2'-(ethylenedioxy)dianiline-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester
产品描述:
INDO 1-AM is a popular non-invasive UV-excitable calcium indicator. It is the cell-permeable ester derivative of INDO 1. After crossing the cell membrane, INDO 1-AM is rapidly hydrolyzed by cytoplasmic esterases to produce the ratiometric fluorescent calcium indicator INDO 1, which remains trapped within the cell. INDO 1/AM has been used to selectively monitor Ca2+ levels in mitochondria and in the cytosol. INDO 1 is ideal for analyses using flow cytometry, as it uses a single excitation source (usually the 351-364nm spectral lines of the argon-ion laser). In contrast to FURA 1, INDO 1 has a dual emission peak. The emission of INDO 1 shifts to 400nm (when bound to Ca2+) from 480nm in Ca2+-free environments. INDO 1 is prone to photobleaching, which limits its usefulness in methods involving microscopy. Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding Ca2+ have enabled researchers to investigate changes in intracellular free Ca2+ concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Spectral Data: lambdaex 330nm; lambdaem 450nm (with Calcium), lambdaex 356nm; lambdaem 478nm in methanol.
宿主来源:
Synthetic.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
1009.93
产品形式:
solid
产地:
瑞士
纯度:
>90% (HPLC)
CAS号:
112926-02-0
分子式:
C47H51N3O22
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