Indomethacin N-octyl amide-抑制剂-深圳欣博盛生物科技有限公司

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Indomethacin N-octyl amide

品牌：Cayman

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说明书

折扣/货期

货号：70273-1 mg	规格：1 mg	目录价：￥350
货号：70273-10 mg	规格：10 mg	目录价：￥2604
货号：70273-5 mg	规格：5 mg	目录价：￥1498
货号：70273-50 mg	规格：50 mg	目录价：￥11298

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Indomethacin N-octyl amide

产品描述:

Indomethacin is a potent but non-selective inhibitor of both COX-1 and COX-2 in sheep and humans.{1286} Structurally, indomethacin is a substituted indole acetic acid, wherein the carboxylate can be derivitized as an ester or amide. These derivatives show enhanced selectivity for the COX-2 isoform. For example, the IC50 values of indomethacin N-octyl amide for the inhibition of ovine COX-1 and human recombinant COX-2 are 66 µM and 40 nM, respectively, making it 1,650 times more potent as an inhibitor of COX-2 than COX-1.{8243} While indomethacin itself has an IC50 of 0.05 µM for the inhibition of COX-2, it also inhibits COX-1 with a corresponding IC50 of 0.67 µM.

保存温度:

-20

运输温度:

-20

预期分子量:

469

产品形式:

A crystalline solid

有效期:

1460

纯度:

≥98%