深圳欣博盛生物科技有限公司 a1

INS Antibody
品牌:ProSci LLC
货号:18-492 规格:100 uL 目录价:¥7651.8
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
INS Antibody
别名:
INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
WB,IHC,IF
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at -20˚C. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
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