| 货号:44645-10 mg | 规格:10 mg | 目录价:¥1889.4 |
| 货号:44645-25 mg | 规格:25 mg | 目录价:¥3470.6 |
| 货号:44645-5 mg | 规格:5 mg | 目录价:¥991.6 |
| 货号:44645-50 mg | 规格:50 mg | 目录价:¥5453.8 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
IQ-3
产品描述:
A JNK inhibitor; selective for JNKs over a panel of 131 kinases at 10 µM; binds to JNKs (Kd = 0.24, 0.29, and 0.066 µM for JNK1-3), as well as CK1δ, PI3Kγ, and MKNK2 (Kds = 0.56, 0.43, and 1.2 µM, respectively); inhibits NF-κB/AP-1 (IC50 = 1.4 µM in a reporter assay); reduces TNF-α and IL-6 production in human Mono-Mac-6 cells (IC50s = 2.2 and 1.5 µM, respectively) and isolated human PBMCs (IC50s = 4.7 and 9.1 µM, respectively), as well as NO production in murine J774A.1 macrophages (IC50 = 6.4 µM)
保存温度:
-20
运输温度:
-20
预期分子量:
341.326
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
312538-03-7
分子式:
C20H11N3O3
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