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折扣/货期| 货号：2213-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：2213-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IRAK-2 Antibody
别名:
IRAK-2 Antibody: IRAK-2, Interleukin-1 receptor-associated kinase-like 2, IRAK-2
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA,WB,IF
靶标/特异性:
Anti-IRAK2 has no cross response to IRAK.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
IRAK-2 Antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/ml
保存温度:
IRAK-2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
IRAK-2 Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
IRAK-2 Antibody: The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF-κB, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK2. Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-κB activation. IRAKs also associate with Toll-like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LPS-induced NF-κB activation. Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory responses to cytokine IL-1 and LPS. IRAK2 is expressed in a variety of human tissues.
Accession #:
AF026273
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