深圳欣博盛生物科技有限公司 a1

IRAK4 Antibody
货号:R31042 规格:100 ug 目录价:¥6488.05
产品详情
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产品名称:
IRAK4 Antibody
产品描述:
Interleukin-1 receptor-associated kinase 4, also called REN64, is an IRAK family protein kinase involved in signaling innate immune responses from Toll-like receptors. It also supports signaling from T-cell receptors. Scott(2002) mapped the gene to chromosome 12 based on similarity between the REN64 sequence(GenBank AF155118) and a chromosome 12 clone(GenBank AC093012). Functional analysis by Li et al.(2002) determined that IRAK4, like IRAK1 and Pelle, has auto- and cross-phosphorylation kinase activity. Precipitation and binding analyses showed weak interaction between IRAK4 and IRAK1, but IRAK4 did not interact with other IRAK family members. Overexpressed protein interacted with MYD88 and TRAF6 and activated mitogen-activated protein kinase (MAPK) and nuclear factor kappa-B (NFKB) pathways.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit IgG
免疫原:
An amino acid sequence from the N-terminus of human Interleukin-1 receptor-associated kinase 4 (DDRYNQFHIRRFEAL) was used as the immunogen for this IRAK4 antibody (100% homologous in human, mouse and rat).
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity
保存温度:
After reconstitution, the IRAK4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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