Irf3 Antibody / Interferon regulatory factor 3-单抗-深圳欣博盛生物科技有限公司

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Irf3 Antibody / Interferon regulatory factor 3

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ6375

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Irf3 Antibody / Interferon regulatory factor 3

产品描述:

IRF3 (interferon regulatory factor 3) is a member of the interferon regulatory transcription factor (IRF) family. The IRF3 gene is mapped on 19q13.33. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. IRF3 plays an important role in the innate immune system's response to viral infection. Aggregated MAVS have been found to activate IRF3 dimerization. Although IRF3 increased transcriptional activity from an ISRE-containing promoter, expression of IRF3 as a Gal4 fusion protein did not activate expression of a chloramphenicol acetyltransferase (CAT) reporter gene containing repeats of the Gal4-binding sites. Translocation of IRF3 was accompanied by an increase in serine and threonine phosphorylation. The transcriptional activators CREBBP and EP300 coimmunoprecipitated with IRF3 only subsequent to viral infection, and the authors stated that these are also subunits of DRAF1.

反应种属:

Mouse, Rat

宿主来源:

Mouse

实验应用:

WB, IF, FACS

同种型:

Mouse IgG2b

免疫原:

Recombinant mouse protein (amino acids M1-I419) was used as the immunogen for the Irf3 antibody.

克隆性:

Monoclonal (mouse origin)

克隆号:

7B10

纯化方式:

Antigen affinity purified

保存温度:

After reconstitution, the Irf3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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