ISG15 Antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

ISG15 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：F41499-0.08ML	规格：0.08 ml	目录价：￥2962.25
货号：F41499-0.4ML	规格：0.4 ml	目录价：￥6343.55

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

ISG15 Antibody

产品描述:

ISG15 is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity. Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega , but not IFN-gamma . ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus. ISG15 is secreted also by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins. The induction of terminal differentiation in human melanoma cells is associated with alterations in ISG15 expression. Enhancement of NK cell proliferation, augmentation of non-major histocompatibility complex-restricted cytotoxicity, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta. ISG15 has has also been shown to function intracellularly as a ubiquitin homolog.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, ELISA

同种型:

Rabbit Ig

免疫原:

A portion of amino acids 136-165 from the human protein was used as the immunogen for this ISG15 antibody.

克隆性:

Polyclonal (rabbit origin)