| 货号:24913-1 mg | 规格:1 mg | 目录价:¥375 |
| 货号:24913-10 mg | 规格:10 mg | 目录价:¥1849 |
| 货号:24913-25 mg | 规格:25 mg | 目录价:¥3685 |
| 货号:24913-5 mg | 规格:5 mg | 目录价:¥1206 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Isosilybin
别名:
Isosilibinin|Isosilybinin|Silybin B
产品描述:
A flavanolignan with antioxidant and anticancer activities; inhibits lipid peroxidation in rat liver microsomes (IC50 = 32 μM); inhibits the production of ROS, MDA and LDH release, and reduction in total antioxidant capacity induced by Aβ25-35 in HT-22 hippocampal cells; increases protein and mRNA expression of HO-1, GST, AKCR1C1, and AKCR1C2 in HT-22 cells; reduces tumor volume and increases tumor cell apoptosis in a DU145 prostate cancer mouse xenograft model at 50 and 100 mg/kg; reduces expression of tumor angiogenesis markers CD31, nestin, VEGF, VEGFR1, VEGFR2, phosphor-Akt, and HIF-1α in tumor tissue without reducing blood vessel count in non-cancerous liver, lung, and kidney tissue in DU145 tumor bearing mice
保存温度:
-20
运输温度:
-20
预期分子量:
482.43618
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
72581-71-6
分子式:
C25H22O10
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