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折扣/货期| 货号：8367-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：8367-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
JAGN1 Antibody
别名:
Jagunal homolog 1
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
ELISA,WB,IHC-P
靶标/特异性:
JAGN1 antibody is human, mouse and rat reactive. At least four isoforms of JAGN1 are known to exist; this antibody will detect all but isoform 2.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
JAGN1 antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
JAGN1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
JAGN1 antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
JAGN1 is the human ortholog of a gene originally identified in Drosophila melanogaster. It is a transmembrane protein that functions in the early secretory pathway and is necessary for neutrophil differentiation and survival. Individuals with mutations in the JAGN1 gene causes aberrant myeloid cell homeostasis and severe congenital neutropenia (SCN) (1). JAGN1-mutant granulocytes are characterized by ultrastructural defects, aberrant N-glycosylation of multiple proteins, and increased apoptosis (1). Mice lacking this gene could not mount and efficient neutrophil-dependent immune response to a human fungal pathogen (2).
Accession #:
NP_115881
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