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折扣/货期| 货号：39387-1 mg | 规格：1 mg | 目录价：￥737 |
| 货号：39387-10 mg | 规格：10 mg | 目录价：￥5159 |
| 货号：39387-5 mg | 规格：5 mg | 目录价：￥2948 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
JAK Inhibitor 31
别名:
Janus-Associated Kinase Inhibitor 31
产品描述:
A JAK2 inhibitor (IC50 = 3.9 nM); selective for JAK2 over JAK3 (IC50s = 70 nM), as well as Aurora B kinase, VEGFR2, Abl1, and GSK3β (IC50s = 0.441, 1.5, 21.37, and 50 µM, respectively), but does inhibit JAK1 and TYK2 (IC50s = 7 and 2.9 nM, respectively); inhibits STAT3-mediated transcription of IL6 in a SEAP reporter assay (IC50 = 162 nM); reduces ocular inflammation, as well as decreases Il6 expression in the meibomian glands, in a mouse model of allergic eye disease at 1 and 3 mg/ml
保存温度:
-20
运输温度:
-20
预期分子量:
398.52966
产品形式:
A solid
纯度:
≥98%
CAS号:
2891469-99-9
分子式:
C19H26N8S
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