JMJD4 Antibody-多抗-深圳欣博盛生物科技有限公司

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JMJD4 Antibody

品牌：NSJ Bio

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说明书

折扣/货期

货号：F40005-0.08ML	规格：0.08 ml	目录价：￥2962.25
货号：F40005-0.4ML	规格：0.4 ml	目录价：￥6343.55

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

JMJD4 Antibody

产品描述:

Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, ELISA

同种型:

Rabbit Ig

免疫原:

A portion of amino acids 1-30 from the human protein was used as the immunogen for this JMJD4 antibody.

克隆性:

Polyclonal (rabbit origin)