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折扣/货期| 货号：14088-1 mg | 规格：1 mg | 目录价：￥1206 |
| 货号：14088-10 mg | 规格：10 mg | 目录价：￥5253 |
| 货号：14088-5 mg | 规格：5 mg | 目录价：￥2935 |
| 货号：14088-50 mg | 规格：50 mg | 目录价：￥11645 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
JNJ-26481585 (hydrochloride)
别名:
Quisinostat
产品描述:
A pan-HDAC inhibitor; inhibits class I (IC50s = 0.11-4.86 nM for HDAC1-3 and HDAC8, respectively), inhibits class IIa (IC50s = 0.64-119 nM for HDAC4-5 and HDAC7-9), and class IIb HDACs (IC50s = 76.8 and 0.46 nM for HDAC6 and HDAC10, respectively), as well as the class IV HDAC HDAC11 (IC50 = 0.37 nM); induces apoptosis, pyroptosis, and ferroptosis in CAL-27 and Tca8113 cells at 200 nM; completely inhibits tumor growth in HCT116 Ras mutant and C170HM2 mouse xenograft models at 10 mg/kg once per day
保存温度:
-20
运输温度:
-20
预期分子量:
394.47038
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
875320-31-3
分子式:
C21H26N6O2 • 2HCl
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