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折扣/货期| 货号：18407-1 mg | 规格：1 mg | 目录价：￥1005 |
| 货号：18407-10 mg | 规格：10 mg | 目录价：￥3953 |
| 货号：18407-25 mg | 规格：25 mg | 目录价：￥8643 |
| 货号：18407-5 mg | 规格：5 mg | 目录价：￥2251.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
JNJ-31020028
产品描述:
An antagonist of NPY receptor Y2 (IC50s = 8.51, 6.03, and 6.17 nM for human, rat, and mouse receptors, respectively); 100-fold selective for Y2 over Y1, Y4, and Y5 receptors; inhibits calcium release induced by peptide YY in a functional assay in KAN-TS cells (pKB = 8.04); blocks NPY(13-36)-induced decreases in twitch contraction amplitude in isolated rat vas deferens (IC50 = 7.94 nM); reverses nicotine-induced social anxiety-like behavior in rats when administered during abstinence at a dose of 20 mg/kg per day, i.p., and increases hippocampal Y2 receptor mRNA levels; reverses withdrawal-induced anxiety-like behavior in rats from a single bolus dose of alcohol in the elevated plus maze when used at a dose of 15 mg/kg, s.c.; chronic administration in an olfactory bulbectomized rat model of depression decreases immobility time in the forced swim test but has no effect in control animals when used at a dose of 10 nmol per day, i.c.v.
保存温度:
-20
运输温度:
-20
预期分子量:
565.7
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
1094873-14-9
分子式:
C34H36FN5O2
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