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折扣/货期| 货号：41361-10 mg | 规格：10 mg | 目录价：￥4409 |
| 货号：41361-100 mg | 规格：100 mg | 目录价：￥14673 |
| 货号：41361-5 mg | 规格：5 mg | 目录价：￥2935 |
| 货号：41361-50 mg | 规格：50 mg | 目录价：￥11738 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
JNJ-38158471
产品描述:
A VEGFR2 inhibitor (IC50 = 42 nM); selective for VEGFR2 over FMS, PDGFRα, FLT3, and KIT (IC50s = 624, 1,109 nM, 4,810, and 511 nM, respectively) and VEGFR1 and VEGFR3 (IC50s = 4,451 and 1,112 nM, respectively) but does inhibit RET (IC50 = 183 nM); decreases VEGF-induced phosphorylation of VEGFR2 in serum-starved HUVECs at 10, 100, or 500 nM; inhibits VEGF-induced migration in HUVECs at 1 µM; reduces Vegf-induced corneal neovascularization in mice at 100 mg/kg; decreases tumor size in an HCT116 mouse xenograft model at 10-200 mg/kg per day; reduces polyp number in an Apc+/Min-FCCC mouse model of spontaneous colorectal adenoma at 100 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
364.78682
产品形式:
A solid
纯度:
≥98%
CAS号:
951151-97-6
分子式:
C15H17ClN6O3
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