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折扣/货期| 货号：41084-10 mg | 规格：10 mg | 目录价：￥2640 |
| 货号：41084-25 mg | 规格：25 mg | 目录价：￥6244 |
| 货号：41084-5 mg | 规格：5 mg | 目录价：￥1394 |
| 货号：41084-50 mg | 规格：50 mg | 目录价：￥11095 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
JNJ-39758979
产品描述:
A histamine H4 receptor antagonist (Ki = 12.5 nM for the human receptor); selective for the histamine H4 receptor over histamine H1, H2, and H3 receptors (Kis = >1,000, >1,000, and 1,043 nM, respectively, for the human receptors), as well as 48 other receptors, ion channels, and transporters at 1 µM and 66 kinases at 10 µM; inhibits histamine-induced chemotaxis of isolated mouse bone marrow-derived mast cells (IC50 = 8 nM); reduces ovalbumin-induced BALF eosinophil infiltration in an ovalbumin-sensitized mouse model of asthma from 0.2-20 mg/kg; decreases ear edema in a mouse model of FITC-induced contact hypersensitivity and inhibits histamine-induced pruritis in mice at 20 mg/kg; reduces nephropathy, but does not affect body weight or blood glucose levels, in a mouse model of STZ-induced diabetes at 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
221.30226
产品形式:
A solid
纯度:
≥98%
CAS号:
1046447-90-8
分子式:
C11H19N5
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