深圳欣博盛生物科技有限公司 a1

K-604 (hydrochloride)
货号:41119-1 mg 规格:1 mg 目录价:¥523
货号:41119-10 mg 规格:10 mg 目录价:¥3095
货号:41119-25 mg 规格:25 mg 目录价:¥5159
货号:41119-5 mg 规格:5 mg 目录价:¥1688
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
K-604 (hydrochloride)
产品描述:
An ACAT-1 inhibitor (IC50 = 0.45 µM); selective for ACAT-1 over ACAT-2 (IC50 = 102.85 µM); reduces cholesterol esterification in monocyte-derived macrophages (IC50 = 0.068 µM); decreases lipid-accumulation areas in the aortic arch in atherosclerosis-susceptible Bio F1B hamsters fed a high-fat and high-cholesterol diet at 10 mg/kg and reduces plasma total cholesterol levels in the same model at 10 and 30 mg/kg; increases autophagosome formation in N2a cells at 0.1 and 1 µM; decreases wild-type and mutant P301L-tau levels in N2a cells overexpressing these proteins but does not affect endogenous tau levels; intranasal administration reduces the level of brain cholesteryl esters in mice at 105 µg/animal
保存温度:
-20
运输温度:
-20
预期分子量:
502.714
产品形式:
A solid
纯度:
≥98%
分子式:
C23H30N6OS3 • 4HCl
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