| 货号:SBB-UP0061-C025 | 规格:25 ug | 目录价:¥3332 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
K6-linked Tetra-Ubiquitin (human) (rec.) (untagged)
别名:
Ub4
产品描述:
The array of cellular processes initiated and regulated by ubiquitin has been partially explained by the structural diversity of differently linked ubiquitin chains. In a ubiquitin chain, ubiquitin moieties can be conjugated through one of their lysine residues (K6, K11, K27, K29, K33, K48 and K63) or the N-terminal methionine residue (M1), offering countless possibilities to assemble a specific polymer. Ubiquitin molecules can also be modified by other post-translational modifications, including acetylation and phosphorylation, adding another layer of ubiquitin signal regulation and diversification. K6-linked ubiquitin linkages are found at increased levels in response to UV radiation, indirectly associated with DNA repair, and have been identified on mitochondrial outer membrane (MOM) proteins. This protein is formed with wild-type human recombinant ubiquitin and linkage-specific enzymes. Ideal for investigating ubiquitin-binding proteins and as substrates for ubiquitin-specific isopeptidases. Reaction conditions will need to be optimized for each specific application.
宿主来源:
E. coli
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~34kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.5.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
上一个:K6-linked Di-Ubiquitin (human) (rec.) (untagged)
下一个:K11-linked Di-Ubiquitin (human) (rec.) (untagged)
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