深圳欣博盛生物科技有限公司 a1

K882
货号:43422-1 mg 规格:1 mg 目录价:¥482.4
货号:43422-10 mg 规格:10 mg 目录价:¥4020
货号:43422-25 mg 规格:25 mg 目录价:¥8844
货号:43422-5 mg 规格:5 mg 目录价:¥2144
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
K882
产品描述:
An inhibitor of Src kinase; binds to Src (Kd = 315 nM), decreases phosphorylation at the Y416 activation site, and increases phosphorylation at the Y527 inactivation site; reduces the proliferation of wild-type NCI H358 cells and KRASG12C-expressing NCI H358 cells (IC50s = 2.14 and 2.03 µM, respectively); inhibits migration and invasion of NCI H358 cells at 2, 4, and 8 µM, induces cell cycle arrest in the G2/M phase at 1, 4, and 8 µM, and induces apoptosis at 4 and 8 µM; reduces tumor volume in an NCI H358 mouse xenograft model at 25, 50, and 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
292.338
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
分子式:
C18H16N2O2
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