| 货号:F54703-0.08ML | 规格:0.08 ml | 目录价:¥2962.25 |
| 货号:F54703-0.4ML | 规格:0.4 ml | 目录价:¥6343.55 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
KCNIP3 Antibody / Calsenilin / KChIP3
产品描述:
KChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes.
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
IF, IHC-P, WB
同种型:
Rabbit Ig
免疫原:
A portion of amino acids 1-30 from the human protein was used as the immunogen for the KCNIP3 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Purified
保存温度:
Aliquot the KCNIP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
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