深圳欣博盛生物科技有限公司 a1

KRCA 0008
货号:43933-10 mg 规格:10 mg 目录价:¥844.2
货号:43933-25 mg 规格:25 mg 目录价:¥1996.6
货号:43933-5 mg 规格:5 mg 目录价:¥442.2
货号:43933-50 mg 规格:50 mg 目录价:¥3323.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
KRCA 0008
产品描述:
An inhibitor of ALK and TNK2 (IC50s = 12 and 4 nM, respectively); selective for these kinases over InsR (IC50 = 210 nM); inhibits ALKL1196M, ALKC1156Y, ALKF1174L, and ALKR1275Q (IC50s = 75, 4, 171, and 17 nM, respectively); selectively reduces the proliferation of NCI H3122 cells, which are driven by the EML4-ALK fusion protein, over NCI H1993 cells, which are driven by c-Met (IC50s = 80 and 3,600 nM, respectively); reduces tumor volume in an NCI H3122 mouse xenograft model at 25 and 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
609.128
产品形式:
A solid
纯度:
≥95%
CAS号:
1472795-20-2
分子式:
C30H37ClN8O4
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