| 货号:42098-1 mg | 规格:1 mg | 目录价:¥576 |
| 货号:42098-10 mg | 规格:10 mg | 目录价:¥4610 |
| 货号:42098-25 mg | 规格:25 mg | 目录价:¥10077 |
| 货号:42098-5 mg | 规格:5 mg | 目录价:¥2600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
KU-0058948
产品描述:
A PARP1 and PARP2 inhibitor (IC50s = 3.4 and 1.5 nM, respectively); selective for PARP1 over PARP3, PARP4, and tankyrase (IC50s = 40, 1,200, and >10,000 nM, respectively); selectively inhibits the survival of embryonic stem cells lacking Brca1 or Brca2 over embryonic stem cells expressing wild-type Brca1 or Brca2; decreases the survival and induces apoptosis in P39 and MUTZ-3 AML cells at 1 µM; potentiates MS-275-induced cytotoxicity in patient-derived AML cells at 5 nM; reduces survival in PTEN-deficient HCT116 cells but not those expressing wild-type PTEN or HCT116+/neo
保存温度:
-20
运输温度:
-20
预期分子量:
380.415603
产品形式:
A solid
纯度:
≥95%
CAS号:
763111-49-5
分子式:
C21H21FN4O2
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