官网链接
折扣/货期| 货号：RQ6389 | 规格：100 ug | 目录价：￥6488.05 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ku70/XRCC6 Antibody
产品描述:
XRCC6 (X-Ray Repair, Complementing Defective, In Chinese Hamster, 6), also called Ku70, G22P1 or TLAA, is a protein that in humans, is encoded by the XRCC6 gene. In addition, the XRCC6 gene encodes subunit p70 of the p70/p80 autoantigen which consists of 2 proteins of molecular mass of approximately 70,000 and 80,000 daltons that dimerize to form a 10 S DNA-binding complex. The XRCC6 gene is mapped to 22q13.2. XRCC6 and Mre11 are differentially expressed during meiosis. XRCC6 interacts with Baxa, a mediator of mitochondrial-dependent apoptosis. Disruption of both FANCC and XRCC6 suppressed sensitivity to crosslinking agents, diminished chromosome breaks, and reversed defective homologous recombination. Ku70 binds directly to free DNA ends, committing them to NHEJ repair. In early meiotic prophase, however, when meiotic recombination is most probably initiated, Mre11 was abundant, whereas XRCC6 was not detectable.
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC-P, IF, FACS
同种型:
Mouse IgG1
免疫原:
Amino acids AIVEKLRFTYRSDSFENPVLQQHFRNLEALALD were used as the immunogen for the Ku70/XRCC6 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
3D7
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the Ku70/XRCC6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
您可能感兴趣的产品
sPLA2 (human Type XIIA) Monoclonal Antibody (Clone 44)
货号：45742
HLA-DR (human) Immunoaffinity Resin (Clone L243)
货号：44917
Clusterin Monoclonal (Clone 9E2E2)
货号：37066
H2AX Phospho-Ser 139 (1H2) Monoclonal Antibody
货号：G01106.100 µL
TLF (TBP like factor) Monoclonal Antibody
货号：G01105.100 µL
TIF2 Monoclonal Antibody
货号：G01104.100 µL
TIF2 Monoclonal Antibody
货号：G01103.100 µL
TIF1δ(Transcriptional intermediary factor 1d) Monoclonal Antibody
货号：G01102.100 µL
促销活动
复制QQ号成功，请打开QQ后添加好友进行咨询