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折扣/货期| 货号：22418-1 mg | 规格：1 mg | 目录价：￥657 |
| 货号：22418-10 mg | 规格：10 mg | 目录价：￥5038 |
| 货号：22418-25 mg | 规格：25 mg | 目录价：￥10211 |
| 货号：22418-5 mg | 规格：5 mg | 目录价：￥2707 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
KW 2478
产品描述:
An Hsp90 inhibitor (IC50 = 3.8 nM for Hsp90α); inhibits the growth of OPM-2/GFP, KMS011, RPMI 8226, and NCI-H929 multiple myeloma cells (GI50s = 0.3, 0.34, 0.39, and 0.12 μM, respectively) and Raji, SR, and SC-1 non-Hodgkin's lymphoma cells (GI50s = 0.39, 0.098, and 0.33 μM, respectively); decreases expression of IGF-IRβ and c-RAF-1 and induces apoptosis in OPM-2/GFP and NCI-H929 cells; reduces IGF-IRβ, c-RAF-1, Cdk9, and phosphorylated ERK1/2 protein levels in tumor tissue and decreases tumor growth in an NCI-H929 mouse xenograft model at 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
574.7
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
819812-04-9
分子式:
C30H42N2O9
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