深圳欣博盛生物科技有限公司 a1

L-732,138
货号:30894-10 mg 规格:10 mg 目录价:¥1608
货号:30894-100 mg 规格:100 mg 目录价:¥11416.8
货号:30894-5 mg 规格:5 mg 目录价:¥924.6
货号:30894-50 mg 规格:50 mg 目录价:¥6177.4
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
L-732,138
产品描述:
An NK1 receptor antagonist (IC50 = 1.6 nM in CHO cells expressing the human receptor); selective for NK1 over NK2 and NK3 receptors (IC50s = >5,000 nM for both); inhibits the growth of COLO 858, MEL HO, and COLO 679 melanoma cells (IC50s = 44.6, 76.3, and 64.2 μM, respectively), as well as induces apoptosis in these cell lines; inhibits plasma extravasation induced by substance P in guinea pigs (ID50 = 8 mg/kg, i.p.); attenuates mechanical allodynia and cold hyperalgesia in a rat model of neuropathic pain induce by chronic constriction injury of the sciatic nerve
保存温度:
-20
运输温度:
-20
预期分子量:
472.380419
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
148451-96-1
分子式:
C22H18F6N2O3
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