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折扣/货期| 货号：32504-10 mg | 规格：10 mg | 目录价：￥2117.2 |
| 货号：32504-25 mg | 规格：25 mg | 目录价：￥4676.6 |
| 货号：32504-5 mg | 规格：5 mg | 目录价：￥1206 |
| 货号：32504-50 mg | 规格：50 mg | 目录价：￥7008.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
L-778,123
产品描述:
A dual inhibitor of FTase and GGTase I (IC50s = 2 and 98 nM, respectively); inhibits prenylation of FTase and GGTase I substrates HDJ2 and Rap1a in PSN-1 pancreatic tumor cells (EC50s = 92 and 6,760 nM, respectively); inhibits prenylation of the oncogenic protein Ki-Ras in PSN-1 cells in a concentration-dependent manner; reduces HDJ2 and Rap1a prenylation ex vivo in dog PBMCs when administered at a dose of 35-50 mg/kg per day; has no effect on Ki-Ras prenylation in patient-derived PBMCs; inhibits lectin-induced expression of the T cell activation markers CD71 and CD25 on human PMBCs (IC50s = 6.48 and 84.1 μM, respectively); inhibits IL-2-induced proliferation of CTLL2 cells (IC50 = 0.81 μM)
保存温度:
-20
运输温度:
-20
预期分子量:
405.88
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
183499-57-2
分子式:
C22H20ClN5O
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