LAG3 Antibody-多抗-深圳欣博盛生物科技有限公司

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LAG3 Antibody

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：8655-0.02 mg	规格：0.02 mg	目录价：￥1345.5
货号：8655-0.1 mg	规格：0.1 mg	目录价：￥6084

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

LAG3 Antibody

别名:

LAG3 Antibody: lymphocyte activating 3, LAG-3, CD223

反应种属:

Human,Mouse

宿主来源:

Rabbit

实验应用:

ELISA,WB,IHC-P,IF

靶标/特异性:

At least two antibodies are known to exist; this antibody will only detect the largest isoform.

同种型:

IgG

克隆性:

Polyclonal

纯化方式:

LAG3 Antibody is affinity chromatography purified via peptide column.

偶联:

Unconjugated

产品浓度:

1 mg/mL

保存温度:

LAG3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

LAG3 Antibody is supplied in PBS containing 0.02% sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy (5).

Accession #:

NP_002277

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