深圳欣博盛生物科技有限公司 a1

Laquinimod
货号:24187-1 g 规格:1 g 目录价:¥8482
货号:24187-100 mg 规格:100 mg 目录价:¥1085
货号:24187-250 mg 规格:250 mg 目录价:¥2546
货号:24187-500 mg 规格:500 mg 目录价:¥4784
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Laquinimod
别名:
ABR-215062
产品描述:
An orally bioavailable immunomodulator; induces expression of genes related to antigen presentation and inflammatory pathways in human PBMCs in vitro (0.1 μM); decreases the severity of symptoms by 91.4% and the number of relapses in mouse models of aEAE and crEAE, respectively (5 mg/kg per day); decreases T cell and macrophage density and demyelination in the spinal cord of EAE mice compared to non-treated controls (5 mg/kg per day); decreases inflammatory lesions and demyelination in the sciatic nerve in a rat EAN model (12.5 and 25 mg/kg per day); activates gene expression in the AhR pathway in splenocytes from EAE mice with no effect in AhR knockout mice (25 mg/kg per day)
保存温度:
-20
运输温度:
-20
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
248281-84-7
分子式:
C19H17ClN2O3
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