| 货号:10008432-1 mg | 规格:1 mg | 目录价:¥1050 |
| 货号:10008432-10 mg | 规格:10 mg | 目录价:¥7350 |
| 货号:10008432-25 mg | 规格:25 mg | 目录价:¥17066 |
| 货号:10008432-5 mg | 规格:5 mg | 目录价:¥4466 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Latanoprost (free acid) (L-arginine salt)
别名:
17-phenyl-13,14-dihydro trinor Prostaglandin F2α|PhXA-85
产品描述:
A crystalline solid form of latanoprost (free acid); selectively binds to the FP receptor (Ki = 0.098 µM) over the EP1, EP1, EP3, and EP4 receptors (Kis = 2.06, 39.667, 7.519, and 75 µM, respectively), as well as the DP, IP, and TP receptors (Kis = ≥20, ≥90, and ≥60 µM, respectively); induces phosphoinositide turnover in isolated human ciliary muscle and human trabecular meshwork cells, mouse NIH3T3 fibroblasts, and rat A7r5 vascular smooth muscle cells, which all endogenously express FP receptors (EC50s = 124, 35, 32, and 35 nM, respectively), as well as HEK293 cells expressing human ocular FP receptors (EC50 = 45.7 nM); increases intracellular calcium levels in hEP1-5/293-AEQ17 cells expressing EP1 receptors in an aequorin-based calcium assay (EC50 = 119 nM); induces contraction of isolated cat iris sphincter smooth muscle (EC50 = 29.9 nM)
保存温度:
-20
运输温度:
-20
预期分子量:
564.8
产品形式:
A solid
有效期:
1460
纯度:
≥95%
分子式:
C29H48N4O7
上一个:9,11-methane-epoxy Prostaglandin F1α
下一个:16-phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide
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