深圳欣博盛生物科技有限公司 a1

LDC-1267
货号:29459-1 mg 规格:1 mg 目录价:¥375
货号:29459-10 mg 规格:10 mg 目录价:¥1849
货号:29459-25 mg 规格:25 mg 目录价:¥3685
货号:29459-5 mg 规格:5 mg 目录价:¥1018
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LDC-1267
产品描述:
A TAM family kinase inhibitor (IC50s = 5, 8, and 29 nM for Mer, Tyro3, and Axl, respectively); selective for TAM family kinases over a panel of 456 kinases at 1 μM, but does inhibit Met, Aurora B, LCK, and Src (IC50s = 35, 36, 51, and 338 nM, respectively); inhibits GAS6-induced suppression of proliferation and IFN-γ production in NKG2D-activated NK cells; adoptive transfer of treated NK cells decreases tumor growth but not metastasis in a B16/F10 murine melanoma model; reduces the number of metastases in B16/F10 murine melanoma and 4T1 murine mammary carcinoma models in an NK cell-dependent manner at 20 mg/kg, i.p.
保存温度:
-20
运输温度:
-20
预期分子量:
560.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1361030-48-9
分子式:
C30H26F2N4O5
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