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折扣/货期| 货号：29419-10 mg | 规格：10 mg | 目录价：￥2117 |
| 货号：29419-25 mg | 规格：25 mg | 目录价：￥4677 |
| 货号：29419-5 mg | 规格：5 mg | 目录价：￥1206 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
LDC000067
别名:
LDC067
产品描述:
A Cdk9 inhibitor (IC50 = 44 nM); selective for Cdk9 over Cdk1, -2, -4, -6, and -7 (IC50s = 5.5, 2.44, 9.24, >10, and >10 μM, respectively) and a panel of 28 additional kinases at 10 μM; inhibits P-TEFb-dependent transcription in vitro and de novo RNA synthesis in A549 cells at 10 μM; induces apoptosis in A549 and MCF-7 cancer cells; prevents IL-1β-induced production of MMP-3, MMP-9, MMP-13, IL-6, IL-8, and TNF-α and NF-κB activation in SW 1353 chondrocytes; delays cartilage degeneration in a mouse model of ACLT at 7.5 mg/kg; prevents bone resorption in mouse models of ACLT- or LPS-induced osteoarthritis
保存温度:
-20
运输温度:
-20
预期分子量:
370.42668
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1073485-20-7
分子式:
C18H18N4O3S
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