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折扣/货期| 货号：44278-1 mg | 规格：1 mg | 目录价：￥415 |
| 货号：44278-10 mg | 规格：10 mg | 目录价：￥2693 |
| 货号：44278-25 mg | 规格：25 mg | 目录价：￥5159 |
| 货号：44278-5 mg | 规格：5 mg | 目录价：￥1662 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Lepzacitinib
别名:
ATI-1777
产品描述:
A JAK1 and JAK3 inhibitor (IC50s = 1.5 and 3.6 nM, respectively); selectively inhibits IL-2 induced activation of JAK1/3 over IFN-γ-induced activation of JAK1/2, GM-CSF-induced activation of JAK2, and IL-12-induced activation of JAK2/TYK2 in isolated human PBMCs (IC50s = 19, 97, 794, and 898 nM, respectively); selective for JAK1 and JAK3 over a panel of 214 additional kinases at 1 µM; topical application of a 2% solution inhibits IL-15-induced expression of mRNA encoding CCL8 by 83% in a porcine model of atopic dermatitis
保存温度:
-20
运输温度:
-20
预期分子量:
355.398
产品形式:
A solid
纯度:
≥98%
CAS号:
2321488-47-3
分子式:
C18H21N5O3
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