官网链接
折扣/货期| 货号：45141-1 mg | 规格：1 mg | 目录价：￥469 |
| 货号：45141-10 mg | 规格：10 mg | 目录价：￥2814 |
| 货号：45141-25 mg | 规格：25 mg | 目录价：￥5280 |
| 货号：45141-5 mg | 规格：5 mg | 目录价：￥1876 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Limertinib
别名:
ASK120067
产品描述:
An inhibitor of mutant EGFR; selective for EGFRL858R/T790M, EGFRT790M, and EGFR containing an exon 19 deletion (IC50s = 0.3, 0.5, and 0.5 nM, respectively) over wild-type EGFR (IC50 = 6 nM) and a panel of 258 kinases at 100 nM; inhibits BTK and Itk (IC50s = 2.1 and 0.4 nM, respectively); selectively inhibits the proliferation of H1975, PC-9, and HCC827 cancer cells, which express mutant EGFRs (IC50s = 12, 6, and 2 nM, respectively), over A431, LoVo, and A549 cancer cells, which express wild-type EGFR (IC50s = 388, 1,916, and 1,541 nM, respectively); induces tumor regression in an H1975 NSCLC mouse xenograft model at 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
546.072
产品形式:
A solid
纯度:
≥95%
CAS号:
1934259-00-3
分子式:
C29H32ClN7O2
促销活动
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