深圳欣博盛生物科技有限公司 a1

LIN7C Antibody / Protein lin-7 homolog C
货号:RQ8624 规格:100 ug 目录价:¥6488.05
产品详情
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产品名称:
LIN7C Antibody / Protein lin-7 homolog C
产品描述:
Lin-7 homolog C is a protein that in humans is encoded by the LIN7C gene. LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
反应种属:
Human, Rat
宿主来源:
Rabbit
实验应用:
WB, IHC-P, FACS, ELISA
同种型:
Rabbit IgG
免疫原:
An E.coli-derived human recombinant protein (amino acids M1-A73) was used as the immunogen for the LIN7C antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the LIN7C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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