| 货号:41833-1 mg | 规格:1 mg | 目录价:¥523 |
| 货号:41833-10 mg | 规格:10 mg | 目录价:¥3618 |
| 货号:41833-25 mg | 规格:25 mg | 目录价:¥6459 |
| 货号:41833-5 mg | 规格:5 mg | 目录价:¥2198 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LNP023
别名:
Iptacopan
产品描述:
A CFB inhibitor (IC50 = 10 nM); selective for CFB over a panel of 41 human proteases and 110 other enzymes, receptors, and ion channels (IC50s = >30 µM for all); inhibits zymosan A-induced formation of the membrane attack complex in isolated human blood (IC50 = 150 nM); blocks hemolysis of erythrocytes isolated from patients with paroxysmal nocturnal hemoglobinuria (IC50 = 400 nM); reduces levels of complement factor Ba, -C3d, and -C5a in the joints, levels of inflammatory cell infiltration in joint tissue, and arthritis disease severity in a K/BxN serum transfer-induced mouse model of inflammatory arthritis at 60 mg/kg twice per day; decreases proteinuria and serum levels of urea and creatinine and prevents hair loss and kidney damage in an MRL-lpr mouse model of lupus nephritis at 30 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
422.51678
产品形式:
A solid
纯度:
≥98%
CAS号:
1644670-37-0
分子式:
C25H30N2O4
促销活动
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