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折扣/货期| 货号：25534-10 mg | 规格：10 mg | 目录价：￥1286 |
| 货号：25534-25 mg | 规格：25 mg | 目录价：￥2975 |
| 货号：25534-5 mg | 规格：5 mg | 目录价：￥831 |
| 货号：25534-50 mg | 规格：50 mg | 目录价：￥5132 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Loxiglumide
别名:
CR1505
产品描述:
A CCK receptor antagonist (Kis = 9.1 and 0.33 μM for CCK-8 binding to central and peripheral CCK receptors, respectively); inhibits CCK-8-induced release of acetylcholine from isolated guinea pig gallbladders (IC50 = 10 nM); reduces the invasion of PANC-1 and MiaPaCa-2 human pancreatic cancer cells at 50 μM; reduces DNA synthesis in PC-TI and PC-YY human pancreatic cancer cells (IC50s = 160 and 74 μM, respectively); reduces tumor growth rate in PC-TI and PC-YY mouse xenograft models at 250 mg/kg; toxic to mice (LD50s = 440-500 mg/kg); reduces serum concentrations of CCK, amylase, and lipase as well as tissue hemorrhaging and acinar cell necrosis in a rat model of acute pancreatitis at 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
461.37878
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
107097-80-3
分子式:
C21H30Cl2N2O5
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