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折扣/货期| 货号：27062-1 mg | 规格：1 mg | 目录价：￥375 |
| 货号：27062-10 mg | 规格：10 mg | 目录价：￥2211 |
| 货号：27062-5 mg | 规格：5 mg | 目录价：￥1300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
LOXO-195
别名:
Selitrectinib
产品描述:
An inhibitor of TrkA and TrkC (IC50s = 0.6 and G595R, TrkAG667C, TrkCG623R, and TrkCG696A (IC50s = 2, 9.8, 2.3, and 50 = 1.9 nM); selectively inhibits proliferation of Trk fusion-positive K12, CUTO-3, and MO-91 cell lines (IC50s = ≤5 nM) over Trk fusion-negative cell lines; reduces tumor growth in TrkA-dependent KM12, as well as NIH 3T3 ΔTrkA, ΔTrkA + TrkAG595R, and ΔTrkA + TrkAG667C mouse xenograft models at ≥30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
380.418983
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
2097002-61-2
分子式:
C20H21FN6O
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